Progeston
Brand names,
Progeston
Analogs
Progeston
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Progeston
Chemical_Formula
C22H32O3
Progeston
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Progeston
fda sheet
Progeston
msds (material safety sheet)
Progeston
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Progeston
Molecular Weight
344.488 g/mol
Progeston
Melting Point
220 - 223.5 oC
Progeston
H2O Solubility
22.2mg/L
Progeston
State
Solid
Progeston
LogP
3.606
Progeston
Dosage Forms
Tablets; Depo injection
Progeston
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Progeston
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Progeston
Absorption
Rapidly absorbed from GI tract
Progeston
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Progeston
Patient Information
Progeston
Organisms Affected
Humans and other mammals