Prodasone
Brand names,
Prodasone
Analogs
Prodasone
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Prodasone
Chemical_Formula
C22H32O3
Prodasone
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Prodasone
fda sheet
Prodasone
msds (material safety sheet)
Prodasone
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Prodasone
Molecular Weight
344.488 g/mol
Prodasone
Melting Point
220 - 223.5 oC
Prodasone
H2O Solubility
22.2mg/L
Prodasone
State
Solid
Prodasone
LogP
3.606
Prodasone
Dosage Forms
Tablets; Depo injection
Prodasone
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Prodasone
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Prodasone
Absorption
Rapidly absorbed from GI tract
Prodasone
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Prodasone
Patient Information
Prodasone
Organisms Affected
Humans and other mammals