Ralovera
Brand names,
Ralovera
Analogs
Ralovera
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Ralovera
Chemical_Formula
C22H32O3
Ralovera
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Ralovera
fda sheet
Ralovera
msds (material safety sheet)
Ralovera
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Ralovera
Molecular Weight
344.488 g/mol
Ralovera
Melting Point
220 - 223.5 oC
Ralovera
H2O Solubility
22.2mg/L
Ralovera
State
Solid
Ralovera
LogP
3.606
Ralovera
Dosage Forms
Tablets; Depo injection
Ralovera
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Ralovera
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Ralovera
Absorption
Rapidly absorbed from GI tract
Ralovera
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Ralovera
Patient Information
Ralovera
Organisms Affected
Humans and other mammals