Cycrin
Brand names,
Cycrin
Analogs
Cycrin
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Cycrin
Chemical_Formula
C22H32O3
Cycrin
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Cycrin
fda sheet
Cycrin
msds (material safety sheet)
Cycrin
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Cycrin
Molecular Weight
344.488 g/mol
Cycrin
Melting Point
220 - 223.5 oC
Cycrin
H2O Solubility
22.2mg/L
Cycrin
State
Solid
Cycrin
LogP
3.606
Cycrin
Dosage Forms
Tablets; Depo injection
Cycrin
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Cycrin
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Cycrin
Absorption
Rapidly absorbed from GI tract
Cycrin
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Cycrin
Patient Information
Cycrin
Organisms Affected
Humans and other mammals