Depomedroxyprogesterone acetate
Brand names,
Depomedroxyprogesterone acetate
Analogs
Depomedroxyprogesterone acetate
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Depomedroxyprogesterone acetate
Chemical_Formula
C22H32O3
Depomedroxyprogesterone acetate
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Depomedroxyprogesterone acetate
fda sheet
Depomedroxyprogesterone acetate
msds (material safety sheet)
Depomedroxyprogesterone acetate
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Depomedroxyprogesterone acetate
Molecular Weight
344.488 g/mol
Depomedroxyprogesterone acetate
Melting Point
220 - 223.5 oC
Depomedroxyprogesterone acetate
H2O Solubility
22.2mg/L
Depomedroxyprogesterone acetate
State
Solid
Depomedroxyprogesterone acetate
LogP
3.606
Depomedroxyprogesterone acetate
Dosage Forms
Tablets; Depo injection
Depomedroxyprogesterone acetate
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Depomedroxyprogesterone acetate
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Depomedroxyprogesterone acetate
Absorption
Rapidly absorbed from GI tract
Depomedroxyprogesterone acetate
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Depomedroxyprogesterone acetate
Patient Information
Depomedroxyprogesterone acetate
Organisms Affected
Humans and other mammals