Lunelle
Brand names,
Lunelle
Analogs
Lunelle
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Lunelle
Chemical_Formula
C22H32O3
Lunelle
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Lunelle
fda sheet
Lunelle
msds (material safety sheet)
Lunelle
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Lunelle
Molecular Weight
344.488 g/mol
Lunelle
Melting Point
220 - 223.5 oC
Lunelle
H2O Solubility
22.2mg/L
Lunelle
State
Solid
Lunelle
LogP
3.606
Lunelle
Dosage Forms
Tablets; Depo injection
Lunelle
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Lunelle
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Lunelle
Absorption
Rapidly absorbed from GI tract
Lunelle
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Lunelle
Patient Information
Lunelle
Organisms Affected
Humans and other mammals