Progestalfa
Brand names,
Progestalfa
Analogs
Progestalfa
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Progestalfa
Chemical_Formula
C22H32O3
Progestalfa
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Progestalfa
fda sheet
Progestalfa
msds (material safety sheet)
Progestalfa
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Progestalfa
Molecular Weight
344.488 g/mol
Progestalfa
Melting Point
220 - 223.5 oC
Progestalfa
H2O Solubility
22.2mg/L
Progestalfa
State
Solid
Progestalfa
LogP
3.606
Progestalfa
Dosage Forms
Tablets; Depo injection
Progestalfa
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Progestalfa
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Progestalfa
Absorption
Rapidly absorbed from GI tract
Progestalfa
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Progestalfa
Patient Information
Progestalfa
Organisms Affected
Humans and other mammals