Medroxyprogesteron
Brand names,
Medroxyprogesteron
Analogs
Medroxyprogesteron
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Medroxyprogesteron
Chemical_Formula
C22H32O3
Medroxyprogesteron
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medroxyprogesteron
fda sheet
Medroxyprogesteron
msds (material safety sheet)
Medroxyprogesteron
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medroxyprogesteron
Molecular Weight
344.488 g/mol
Medroxyprogesteron
Melting Point
220 - 223.5 oC
Medroxyprogesteron
H2O Solubility
22.2mg/L
Medroxyprogesteron
State
Solid
Medroxyprogesteron
LogP
3.606
Medroxyprogesteron
Dosage Forms
Tablets; Depo injection
Medroxyprogesteron
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medroxyprogesteron
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medroxyprogesteron
Absorption
Rapidly absorbed from GI tract
Medroxyprogesteron
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medroxyprogesteron
Patient Information
Medroxyprogesteron
Organisms Affected
Humans and other mammals