Progevera
Brand names,
Progevera
Analogs
Progevera
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Progevera
Chemical_Formula
C22H32O3
Progevera
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Progevera
fda sheet
Progevera
msds (material safety sheet)
Progevera
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Progevera
Molecular Weight
344.488 g/mol
Progevera
Melting Point
220 - 223.5 oC
Progevera
H2O Solubility
22.2mg/L
Progevera
State
Solid
Progevera
LogP
3.606
Progevera
Dosage Forms
Tablets; Depo injection
Progevera
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Progevera
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Progevera
Absorption
Rapidly absorbed from GI tract
Progevera
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Progevera
Patient Information
Progevera
Organisms Affected
Humans and other mammals