Farlutin
Brand names,
Farlutin
Analogs
Farlutin
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Farlutin
Chemical_Formula
C22H32O3
Farlutin
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Farlutin
fda sheet
Farlutin
msds (material safety sheet)
Farlutin
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Farlutin
Molecular Weight
344.488 g/mol
Farlutin
Melting Point
220 - 223.5 oC
Farlutin
H2O Solubility
22.2mg/L
Farlutin
State
Solid
Farlutin
LogP
3.606
Farlutin
Dosage Forms
Tablets; Depo injection
Farlutin
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Farlutin
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Farlutin
Absorption
Rapidly absorbed from GI tract
Farlutin
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Farlutin
Patient Information
Farlutin
Organisms Affected
Humans and other mammals