Asconale
Brand names,
Asconale
Analogs
Asconale
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Asconale
Chemical_Formula
C22H32O3
Asconale
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Asconale
fda sheet
Asconale
msds (material safety sheet)
Asconale
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Asconale
Molecular Weight
344.488 g/mol
Asconale
Melting Point
220 - 223.5 oC
Asconale
H2O Solubility
22.2mg/L
Asconale
State
Solid
Asconale
LogP
3.606
Asconale
Dosage Forms
Tablets; Depo injection
Asconale
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Asconale
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Asconale
Absorption
Rapidly absorbed from GI tract
Asconale
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Asconale
Patient Information
Asconale
Organisms Affected
Humans and other mammals