Gestapuran
Brand names,
Gestapuran
Analogs
Gestapuran
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Gestapuran
Chemical_Formula
C22H32O3
Gestapuran
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Gestapuran
fda sheet
Gestapuran
msds (material safety sheet)
Gestapuran
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Gestapuran
Molecular Weight
344.488 g/mol
Gestapuran
Melting Point
220 - 223.5 oC
Gestapuran
H2O Solubility
22.2mg/L
Gestapuran
State
Solid
Gestapuran
LogP
3.606
Gestapuran
Dosage Forms
Tablets; Depo injection
Gestapuran
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Gestapuran
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Gestapuran
Absorption
Rapidly absorbed from GI tract
Gestapuran
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Gestapuran
Patient Information
Gestapuran
Organisms Affected
Humans and other mammals