Medroxiprogesteronum
Brand names,
Medroxiprogesteronum
Analogs
Medroxiprogesteronum
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Medroxiprogesteronum
Chemical_Formula
C22H32O3
Medroxiprogesteronum
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medroxiprogesteronum
fda sheet
Medroxiprogesteronum
msds (material safety sheet)
Medroxiprogesteronum
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medroxiprogesteronum
Molecular Weight
344.488 g/mol
Medroxiprogesteronum
Melting Point
220 - 223.5 oC
Medroxiprogesteronum
H2O Solubility
22.2mg/L
Medroxiprogesteronum
State
Solid
Medroxiprogesteronum
LogP
3.606
Medroxiprogesteronum
Dosage Forms
Tablets; Depo injection
Medroxiprogesteronum
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medroxiprogesteronum
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medroxiprogesteronum
Absorption
Rapidly absorbed from GI tract
Medroxiprogesteronum
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medroxiprogesteronum
Patient Information
Medroxiprogesteronum
Organisms Affected
Humans and other mammals