Hysron
Brand names,
Hysron
Analogs
Hysron
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Hysron
Chemical_Formula
C22H32O3
Hysron
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Hysron
Molecular Weight
344.488 g/mol
Hysron
Melting Point
220 - 223.5 oC
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H2O Solubility
22.2mg/L
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State
Solid
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LogP
3.606
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Dosage Forms
Tablets; Depo injection
Hysron
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Hysron
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Hysron
Absorption
Rapidly absorbed from GI tract
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side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Hysron
Patient Information
Hysron
Organisms Affected
Humans and other mammals