Aragest
Brand names,
Aragest
Analogs
Aragest
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Aragest
Chemical_Formula
C22H32O3
Aragest
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Aragest
fda sheet
Aragest
msds (material safety sheet)
Aragest
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Aragest
Molecular Weight
344.488 g/mol
Aragest
Melting Point
220 - 223.5 oC
Aragest
H2O Solubility
22.2mg/L
Aragest
State
Solid
Aragest
LogP
3.606
Aragest
Dosage Forms
Tablets; Depo injection
Aragest
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Aragest
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Aragest
Absorption
Rapidly absorbed from GI tract
Aragest
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Aragest
Patient Information
Aragest
Organisms Affected
Humans and other mammals