Lutopolar
Brand names,
Lutopolar
Analogs
Lutopolar
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Lutopolar
Chemical_Formula
C22H32O3
Lutopolar
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Lutopolar
fda sheet
Lutopolar
msds (material safety sheet)
Lutopolar
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Lutopolar
Molecular Weight
344.488 g/mol
Lutopolar
Melting Point
220 - 223.5 oC
Lutopolar
H2O Solubility
22.2mg/L
Lutopolar
State
Solid
Lutopolar
LogP
3.606
Lutopolar
Dosage Forms
Tablets; Depo injection
Lutopolar
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Lutopolar
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Lutopolar
Absorption
Rapidly absorbed from GI tract
Lutopolar
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Lutopolar
Patient Information
Lutopolar
Organisms Affected
Humans and other mammals