Categorie
Adrenaline/Epinephrine
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Adrenaline/Epinephrine
Analogs
Adrenaline/Epinephrine
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1% Lidocaine Hydrochloride and Epinephrine 1:100000 Inj Usp (Epinephrine + Lidocaine Hydrochloride) 2% Lidocaine Hydrochloride and Epinephrine 1:100000 Inj Usp (Epinephrine + Lidocaine Hydrochloride) 2% Xylocaine Dental with Epinephrine 1:100,000 (Epinephrine + Lidocaine Hydrochloride) 2% Xylocaine Dental with Epinephrine 1:50,000 (Epinephrine + Lidocaine Hydrochloride) 4% Citanest Forte Dental with Epinephrine 1:200,000 (Epinephrine (Epinephrine Bitartrate) + Prilocaine Hydrochloride) Ad Plex (Celandine + Echinacea Angustifolia + Epinephrine + Lycopodium Clavatum + Milk Thistle + Phosphoric Acid + Propolis + Sodium Chloride) Ad Tonic (Charcoal Activated + Epinephrine + Glycyrrhiza Glabra + Iodine + Lycopodium Clavatum + Oats + Phosphoric Acid + Potassium Phosphate Dibasic + Sarsaparilla + Sodium Chloride) Adaptagen (Capsicum + Charcoal Activated + Conium Maculatum + Copper + Elaeis Guineensis + Epinephrine + Ginkgo Biloba + Ginseng + Glycyrrhiza Glabra + Iodine + Ledum Palustre + Oats + Phosphoric Acid + Picric Acid + Pituitary Posterior + Selenium + Sepia Officinalis L + Silicon Dioxide + Sodium Carbonate (Anhydrous) + Thuja Occidentalis + Vitamin B1 + Vitamin B2) All- I (Charcoal Activated + Epinephrine + Histamine + Liverwort + Lycopodium Clavatum + Phosphorus + Potassium Phosphate Dibasic + Pulsatilla + Silicon Dioxide + Sodium Phosphate Dibasic) All-Ii (Epinephrine + Euphrasia Officinalis + Goldenrod + Histamine + Liverwort + Modified Ragweed Tyrosine Adsorbate + Phosphorus + Potassium Iodide + Pulsatilla + Sulfur) Allforce (Aralia Racemosa + Cantharides + Charcoal Activated + Epinephrine + Ginger + Glycyrrhiza Glabra + Iodine + Onion + Oyster Shells + Phosphorus + Poison Ivy + Sarsaparilla + Sodium Carbonate (Anhydrous)) Alopt (Baptisia Tinctoria + Echinacea Angustifolia + Epinephrine + Euphrasia Officinalis + Garlic + Goldenrod + Histamine + Modified Ragweed Tyrosine Adsorbate + Onion + Phosphorus + Potassium Dichromate + Pulsatilla + Sulfur) Alphacaine Hcl 2% W Epineph 1:100000 (Epinephrine + Lidocaine Hydrochloride) Alphacaine Hcl 2% W Epineph 1:50000 (Epinephrine + Lidocaine Hydrochloride) Ana-Kit (2mg/Tab Orl, 1mg/Ml Liq Sc Im) (Chlorpheniramine Maleate + Epinephrine) Ana-Kit (Chlorpheniramine Maleate + Epinephrine Hcl) Anakit Insect Sting Treatment Kit (Chlorpheniramine Maleate + Epinephrine) Andropt (Astragalus Menziesii + Echinacea Angustifolia + Epinephrine + Juniper Berries + Oats + Phosphoric Acid + Picric Acid + Pulsatilla + Saw Palmetto + Selenium + Sodium Hexafluorosilicate + Thuja Occidentalis + Vitex Agnus Castus) Bac (Astragalus Menziesii + Baptisia Tinctoria + Belladonna + Charcoal Activated + Echinacea Angustifolia + Epinephrine + Ferrum Phosphoricum + Hydrastis Canadensis + Hypericum Perforatum + Iodine + Myrrh + Phosphorus + Phytolacca Decandra + Propolis + Silicon Dioxide + Water Cress) Candopt (Astragalus Menziesii + Echinacea Angustifolia + Epinephrine + Fucus Vesiculosus + Hydrastis Canadensis + Lycopodium Clavatum + Phosphoric Acid + Platanus Occidentalis + Pulsatilla + Sepia Officinalis L + Sodium Chloride) Chemtox (Barberry Root + Belladonna + Burdock + Cascarilla + Charcoal Activated + Couch Grass + Epinephrine + Glycerine + Glycyrrhiza Glabra + Iodine + Liverwort + Lycopodium Clavatum + Nitric Acid + Phosphoric Acid + Phosphorus + Phytolacca Decandra + Pulsatilla + Stillingia + Trifolium Pratense + Xanthoxylum) Crc-Plex (Arnica Montana + Barium Chloride + Calcium Lactate + Charcoal Activated + Cholesterol + Convallaria Majalis + Epinephrine + Iodine + Magnesium Carbonate + Nitroglycerin + Phosphorus + Picric Acid + Potassium Iodide + Strophanthus Hispidus) Cv Tox (Astragalus Menziesii + Barberry Root + Diadem Spider + Echinacea Angustifolia + Epinephrine + Gelsemium Sempervirens + Hydrastis Canadensis + Hydrochloric Acid + Ipecac + Lycopodium Clavatum + Nitric Acid + Phosphoric Acid + Poison Ivy + Scurvy Grass + Silicon Dioxide) E-Pilo 1 Ophthalmic Solution (Epinephrine Bitartrate + Pilocarpine Hydrochloride) E-Pilo 2 Ophthalmic Solution (Epinephrine Bitartrate + Pilocarpine Hydrochloride) E-Pilo 4 Ophthalmic Solution (Epinephrine Bitartrate + Pilocarpine Hydrochloride) E-Pilo 6 Ophthalmic Solution (Epinephrine Bitartrate + Pilocarpine Hydrochloride) E-Pilo-1 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride) E-Pilo-2 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride) E-Pilo-4 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride) E-Pilo-6 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride) Endangitin (Aesculus Hippocastanum + Cupric Acetate + Epinephrine + Ergot + Potentilla Anserina + Tobacco + White Hellebore Root) Endoplex F (Bovine Ovaries, Dried + Charcoal Activated + Cimicifuga Racemosa + Epinephrine + Fucus Vesiculosus + Glycyrrhiza Glabra + Iodine + Murex Purpurea + Pituitary Posterior + Pulsatilla + Sabina + Sepia Officinalis L + Xanthoxylum) Endoplex M (Clematis Erecta + Conium Maculatum + Epinephrine + Ginseng + Juniper Berries + Lycopodium Clavatum + Parsley + Picric Acid + Pituitary Posterior + Pulsatilla + Saw Palmetto + Thuja Occidentalis + Uva Ursi + Vitex Agnus Castus + Xanthoxylum) Ev Tox (Astragalus Menziesii + Belladonna + Charcoal Activated + Diadem Spider + Echinacea Angustifolia + Epinephrine + Hydrastis Canadensis + Hydrochloric Acid + Ipecac + Lycopodium Clavatum + Nitric Acid + Poison Ivy + Propolis + Scurvy Grass + Silicon Dioxide) F Alleropt (Aethusa Cynapium + Belladonna + Capsicum + Charcoal Activated + Comfrey + Echinacea Angustifolia + Epinephrine + Gentiana Cruciata + Histamine + Lycopodium Clavatum + Phosphorus + Potassium Dichromate + Pulsatilla) Fml-Tox (Angelicae Sinensis Radix + Beechwood Creosote + Boric Acid + Cimicifuga Racemosa + Epinephrine + Iodine + Oophorinum + Oyster Shells + Placenta + Pulsatilla + Sepia Officinalis L + Sodium Chloride + Sulfur + Zinc) Fng I (Astragalus Menziesii + Condurango + Echinacea Angustifolia + Epinephrine + Ginkgo Biloba + Hydrastis Canadensis + Lycopodium Clavatum + Phosphoric Acid + Phosphorus + Phytolacca Decandra + Propolis + Sepia Officinalis L + Sodium Chloride + Water Cress) Fng Ii (Astragalus Menziesii + Candida Parapsilosis + Charcoal Activated + Echinacea Angustifolia + Epinephrine + Hydrastis Canadensis + Iodine + Lycopodium Clavatum + Phosphoric Acid + Pulsatilla + Sepia Officinalis L + Silver + Sodium Chloride + Water Cress) Gingibraid W Alum Pot Sulf and Epin 0e (Aluminum Potassium Sulfate + Racemic Epinephrine Hydrochloride) Gingibraid W Epineph and Alum 1e (Aluminum Potassium Sulfate + Racemic Epinephrine Hydrochloride) Gingibraid W Epineph and Alum 2e (Aluminum Potassium Sulfate + Racemic Epinephrine Hydrochloride) Gingibraid W Epineph and Alum 3e (Aluminum Potassium Sulfate + Racemic Epinephrine Hydrochloride) Gingicord W Epineph and Alum Size No 1 (Aluminum Potassium Sulfate + Racemic Epinephrine Hydrochloride) Gingicord W Epineph and Alum Size No 3 (Aluminum Potassium Sulfate + Racemic Epinephrine Hydrochloride) Gingicord W/Epineph and Alum Size 2 (Aluminum Potassium Sulfate + Racemic Epinephrine Hydrochloride) Gynopt (Angelica + Beechwood Creosote + Boric Acid + Bovine Ovaries, Dried + Charcoal Activated + Cimicifuga Racemosa + Epinephrine + Iodine + Nitric Acid + Placenta + Potassium Acetate + Pulsatilla + Sepia Officinalis L + Sodium Chloride + Sulfur) Immplex (Astragalus Menziesii + Calcium Sulfide Crude + Echinacea Angustifolia + Epinephrine + Eupatorium Perfoliatum + Ferrum Phosphoricum + Hydrastis Canadensis + Myrrh + Phosphoric Acid + Propolis + Silicon Dioxide + Water Cress) Lido-2 Liq (Epinephrine Hcl + Lidocaine Hydrochloride) Lidocaine 2% Sterile Injectable Solution (Epinephrine Racemic + Lidocaine Hydrochloride) Lidocaine 2% with Epinephrine 1:100000 (Epinephrine + Lidocaine Hydrochloride) Lidocaine Hcl 2% (Epinephrine + Lidocaine Hydrochloride) Lidocaine Hcl 2% Epinephrine Inj (Epinephrine + Lidocaine Hydrochloride) Lidocaine Hcl 2% W Epineph 1:100000inj (Epinephrine + Lidocaine Hydrochloride) Lidocaine Hcl 2% W Epinephrine (Epinephrine + Lidocaine Hydrochloride) Lidocaine Hcl 2% W Epinephrine 1:100000 (Epinephrine + Lidocaine Hydrochloride) Lidocaine Hcl 2% W Epinephrine 1:50000 (Epinephrine + Lidocaine Hydrochloride) Lidocaine Inj 2% (Epinephrine Hcl + Lidocaine Hydrochloride) Lidocaine and Epinephrine Inj.Usp2% 1:100000 (Epinephrine + Lidocaine Hydrochloride) Lignospan Forte (Epinephrine + Lidocaine Hydrochloride) Lignospan Speciale Inj (Epinephrine + Lidocaine Hydrochloride) Lignospan Standard (Epinephrine + Lidocaine Hydrochloride) Marcaine E 0.25% Liq Prt (Bupivacaine Hydrochloride + Epinephrine Bitartrate) Marcaine E 2.5 Mg/Ml (Bupivacaine Hydrochloride + Epinephrine Bitartrate) Marcaine E 5.0 Mg/Ml (Bupivacaine Hydrochloride + Epinephrine Bitartrate) Marcaine E Liq Prt 0.50% (Bupivacaine Hydrochloride + Epinephrine Bitartrate) Nasal Spray (Echinacea Angustifolia + Epinephrine + Gelsemium Sempervirens + Modified Ragweed Tyrosine Adsorbate + Onion + Potassium Iodide + Sanguinaria Canadensis + Sticta Pulmonaria) Neuplex (Agaricus Muscarius + Arnica Montana + Charcoal Activated + Diadem Spider + Epinephrine + Hypericum Perforatum + Iodine + Passion Flower + Plumbum Metallicum + Trifolium Pratense) Octocaine 100 Needleject Inj (Epinephrine + Lidocaine Hydrochloride) Octocaine Hcl 2% Epinephrine 1:100000inj (Epinephrine Hcl + Lidocaine Hydrochloride) Octocaine Hcl 2% Epinephrine 1:50000inj (Epinephrine Hcl + Lidocaine Hydrochloride) Panplex (Celandine + Charcoal Activated + Common Bean Garden + Epinephrine + Eugenia Jambolana + Ginger + Glycyrrhiza Glabra + Hydrastis Canadensis + Iodine + Liverwort + Nux Moschata + Pancreas + Phosphoric Acid + Phosphorus + Pituitary Posterior + Rhubarb + Taraxacum Officinale Weber) Prilocaine Hcl 4% Epineph 1:200000inj (Epinephrine + Prilocaine Hydrochloride) R63 (Aesculus Hippocastanum + Cupric Acetate + Epinephrine + Potentilla Anserina + Tobacco) Racord Two 7 (Racemic Epinephrine Hydrochloride + Zinc Phenolsulphonate) Racord Two No 10 (Racemic Epinephrine Hydrochloride + Zinc Phenolsulphonate) Racord Two No 8 (Racemic Epinephrine Hydrochloride + Zinc Phenolsulphonate) Racord Two No 9 (Racemic Epinephrine Hydrochloride + Zinc Phenolsulphonate) Radopt (Brassica Napus + Cadmium Iodatum + Cadmium Sulphuricum + Capsicum + Charcoal Activated + Diadem Spider + Epinephrine + Fucus Vesiculosus + Goldenrod + Iodine + Ipecac + Iridium Metallicum + Phosphoric Acid + Phosphorus + Uranium Nitrate + X-Ray) Rdn-Tox (Cadmium Iodatum + Cadmium Sulphuricum + Capsicum + Cetraria Islandica + Charcoal Activated + Epinephrine + Fucus Vesiculosus + Hydrangea Arborescens + Iodine + Phosphoric Acid + Phosphorus + Pulsatilla + Strontium Carbonate + Uranium Nitrate + X-Ray) Scandonest 2% Special Inj (Epinephrine + Mepivacaine Hydrochloride) Sensorcaine 0.25% with Epinephrine (Bupivacaine Hydrochloride + Epinephrine (Epinephrine Bitartrate)) Sensorcaine 0.5% with Epinephrine (Bupivacaine Hydrochloride + Epinephrine (Epinephrine Bitartrate)) Sensorcaine Forte (Bupivacaine Hydrochloride + Epinephrine (Epinephrine Bitartrate)) Septanest N (Articaine Hydrochloride + Epinephrine (Epinephrine Bitartrate)) Septanest Sp (Articaine Hydrochloride + Epinephrine (Epinephrine Bitartrate)) Sil Trax Plus No 10 (Racemic Epinephrine Hydrochloride + Zinc Phenolsulphonate) Sil Trax Plus No 8 (Racemic Epinephrine Hydrochloride + Zinc Phenolsulphonate) Sil Trax Plus No 9 (Racemic Epinephrine Hydrochloride + Zinc Phenolsulphonate) Siltrax Plus 7 (Racemic Epinephrine Hydrochloride + Zinc Phenolsulphonate) Spinal Anaesthesia Tray (Dextrose + Epinephrine + Iodine (Povidone-Iodine) + Lidocaine Hydrochloride + Tetracaine Hydrochloride) Spinal Anaesthesia Tray (Dextrose + Epinephrine + Lidocaine Hydrochloride + Povidone-Iodine + Tetracaine Hydrochloride) Spinal Anesthesia Tray (Dextrose + Ephedrine Sulfate + Epinephrine + Lidocaine Hydrochloride + Tetracaine Hydrochloride) Spinal Anesthesia Tray (Dextrose + Epinephrine + Lidocaine Hydrochloride + Tetracaine Hydrochloride) Super Sulpak R 44 (Aluminum Potassium Sulfate + Racemic Epinephrine Hydrochloride) Super Sulpak R 45 (Aluminum Potassium Sulfate + Racemic Epinephrine Hydrochloride) Super Sulpak R 46 (Aluminum Potassium Sulfate + Racemic Epinephrine Hydrochloride) Systopt (Barberry Root + Burdock + Calcium Sulfide Crude + Celandine + Charcoal Activated + Conium Maculatum + Diadem Spider + Epinephrine + Glycyrrhiza Glabra + Goldenrod + Hydrastis Canadensis + Lycopodium Clavatum + Tarentula Cubensis + Thuja Occidentalis + Trifolium Pratense) Systox (Barberry Root + Boldo + Burdock + Calcium Sulfide Crude + Celandine + Charcoal Activated + Conium Maculatum + Diadem Spider + Epinephrine + Hydrastis Canadensis + Lycopodium Clavatum + Sarsaparilla + Taraxacum Officinale Weber + Tarentula Cubensis + Thuja Occidentalis + Trifolium Pratense) Tyd-Plex (Charcoal Activated + Epinephrine + Ferrous Iodide + Fucus Vesiculosus + Iodine + Oyster Shells + Phosphoric Acid + Pituitary Posterior + Potassium Iodide + Spongia Tosta) Ultracaine D-S Forte Injection (Articaine Hydrochloride + Epinephrine) Ultracaine D-S Injection (Articaine Hydrochloride + Epinephrine) Ultracaine Ds Forte Inj (Articaine Hydrochloride + Epinephrine) Ultracaine Ds Inj (Articaine Hydrochloride + Epinephrine) Universaltox (Alfalfa + Buckthorn + Charcoal Activated + Coffea Tosta + Comfrey + Epinephrine + Fucus Vesiculosus + Iodine + Liverwort + Lycopodium Clavatum + Manganese + Oats + Oyster Shells + Poison Ivy + Pulsatilla + Sepia Officinalis L + Sodium Chloride + Spigelia Anthelmia + Water Cress) Vactox (Arnica Montana + Astragalus Menziesii + Baptisia Tinctoria + Belladonna + Calendula + Celandine + Echinacea Angustifolia + Epinephrine + Gelsemium Sempervirens + German Chamomile + Hydrastis Canadensis + Lycopodium Clavatum + Phytolacca Decandra + Poison Ivy + Propolis + Silicon Dioxide + Taraxacum Officinale Weber + Thuja Occidentalis + Trifolium Pratense + Urtica Urens + Water Cress) Virotox (Astragalus Menziesii + Belladonna + Echinacea Angustifolia + Epinephrine + Eupatorium Perfoliatum + Gelsemium Sempervirens + Hydrastis Canadensis + Lycopodium Clavatum + Myrrh + Phytolacca Decandra + Water Cress) Xylocaine 0.5% W Epinephrine 1:100000 (Epinephrine + Lidocaine Hydrochloride) Xylocaine 0.5% W Epinephrine 1:200000 (Epinephrine + Lidocaine Hydrochloride) Xylocaine 1% W Epinephrine 1:100000 (Epinephrine + Lidocaine Hydrochloride) Xylocaine 1% W Epinephrine 1:200000 (Epinephrine + Lidocaine Hydrochloride) Xylocaine 1.5% W Epinephrine 1:200000 (Epinephrine + Lidocaine Hydrochloride) Xylocaine 1.5% W Epinephrine 1:200000 Test Dose (Epinephrine + Lidocaine Hydrochloride) Xylocaine 2% W Epinephrine 1:100000 (Epinephrine + Lidocaine Hydrochloride) Xylocaine 2% W Epinephrine 1:200000 (Epinephrine + Lidocaine Hydrochloride) Xylocaine Mpf 1.5% with Epinephrine (Epinephrine + Lidocaine Hydrochloride) Zorcaine (Articaine Hydrochloride + Epinephrine (Epinephrine Bitartrate))
Adrenaline/Epinephrine
Formule chimique
C9H13NO3
Adrenaline/Epinephrine
RX lien
http://www.rxlist.com/cgi/generic3/epi.htm
Adrenaline/Epinephrine
FDA fiche
Adrenaline/Epinephrine
msds (fiche de securite des materiaux)
Adrenaline/Epinephrine
Synthese de reference
Stolz, Ber. 37, 4149; Payne, Ind Chem. 37, 523
Adrenaline/Epinephrine
Poids moleculaire
183.204 g/mol
Adrenaline/Epinephrine
Point de fusion
211.5 oC
Adrenaline/Epinephrine
H2O Solubilite
180 mg / L
Adrenaline/Epinephrine
Etat
Solid
Adrenaline/Epinephrine
LogP
0.256
Adrenaline/Epinephrine
Formes pharmaceutiques
Cordon; gouttes, liquide, doseur (aérosol); Pad; Pellet; Pellet (soins dentaires); Solution; pulvérisation
Adrenaline/Epinephrine
Indication
Pour le traitement des réactions anaphylactiques
Adrenaline/Epinephrine
Pharmacologie
L'épinéphrine est indiqué pour l'injection intraveineuse dans le traitement de l'hypersensibilité aiguë, le traitement des crises d'asthme aiguës pour soulager le bronchospasme, et le traitement et la prophylaxie de l'arrêt cardiaque et les attaques de bloc auriculo-ventriculaire transitoire coeur avec des crises de syncope (syndrome de Stokes-Adams). Les actions de l'épinéphrine ressemblent aux effets de la stimulation des nerfs adrénergiques. Pour une variable degrés, il agit sur les deux sites récepteurs alpha et bêta de sympathiques cellules effectrices. Ses actions les plus importantes sont sur les récepteurs bêta du cœur, le muscle lisse vasculaire et d'autres. Lorsqu'il est administré par l'évolution rapide injection intraveineuse, il produit une augmentation rapide de la pression artérielle, surtout systolique, par (1) la stimulation directe du muscle cardiaque qui augmente la force de contraction ventriculaire, (2) l'augmentation du le rythme cardiaque et (3) la constriction des artérioles de la peau, les muqueuses et les zones de la circulation splanchnique. Lorsqu'il est administré en injection intraveineuse lente, l'adrénaline produit habituellement seulement une hausse modérée systolique et une chute de la pression diastolique. Bien que certains augmentation de la pression d'impulsion se produit, il n'est généralement pas une grande élévation de la pression artérielle moyenne. En conséquence, les mécanismes compensatoires réflexes qui entrent en jeu avec une augmentation prononcée de la pression artérielle ne antagoniser l'action directe cardiaques de l'adrénaline autant que les catécholamines qui ont une action prédominante sur les récepteurs alpha. .
Adrenaline/Epinephrine
Absorption
Habituellement cet effet vasodilatateur de la drogue sur la circulation de telle sorte que prédomine la hausse modeste de la pression systolique, qui suit l'injection lente ou de l'absorption est principalement le résultat de la stimulation cardiaque directe et augmentation du débit cardiaque.
Adrenaline/Epinephrine
Toxicite
La peau, LD50 = 62 mg / kg (rat)
Adrenaline/Epinephrine
Information pour les patients
No information avaliable
Adrenaline/Epinephrine
Organismes affectes
Les humains et autres mammifères
