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Ranitidine Brand names, Ranitidine Analogs

Ranitidine Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Ranitidine Chemical_Formula


Ranitidine RX_link


Ranitidine fda sheet

Ranitidine FDA

Ranitidine msds (material safety sheet)

Ranitidine MSDS

Ranitidine Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Ranitidine Molecular Weight

314.405 g/mol

Ranitidine Melting Point

69-70 oC

Ranitidine H2O Solubility

24.7 mg/mL

Ranitidine State


Ranitidine LogP


Ranitidine Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Ranitidine Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Ranitidine Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Ranitidine Absorption

Approximately 50% bioavailability orally.

Ranitidine side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Ranitidine Patient Information


Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Ranitidine Organisms Affected

Humans and other mammals