Zantac In Plastic Container
Brand names,
Zantac In Plastic Container
Analogs
Zantac In Plastic Container
Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Zantac In Plastic Container
Chemical_Formula
C13H22N4O3S
Zantac In Plastic Container
RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Zantac In Plastic Container
fda sheet
Zantac In Plastic Container
msds (material safety sheet)
Zantac In Plastic Container
Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Zantac In Plastic Container
Molecular Weight
314.405 g/mol
Zantac In Plastic Container
Melting Point
69-70 oC
Zantac In Plastic Container
H2O Solubility
24.7 mg/mL
Zantac In Plastic Container
State
Solid
Zantac In Plastic Container
LogP
1.93
Zantac In Plastic Container
Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Zantac In Plastic Container
Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Zantac In Plastic Container
Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Zantac In Plastic Container
Absorption
Approximately 50% bioavailability orally.
Zantac In Plastic Container
side effects and Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Zantac In Plastic Container
Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Zantac In Plastic Container
Organisms Affected
Humans and other mammals