Ranitidine HCL en es it fr

Ranitidine HCL Brand names, Ranitidine HCL Analogs

Ranitidine HCL Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Ranitidine HCL Chemical_Formula


Ranitidine HCL RX_link


Ranitidine HCL fda sheet

Ranitidine_HCL FDA

Ranitidine HCL msds (material safety sheet)

Ranitidine_HCL MSDS

Ranitidine HCL Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Ranitidine HCL Molecular Weight

314.405 g/mol

Ranitidine HCL Melting Point

69-70 oC

Ranitidine HCL H2O Solubility

24.7 mg/mL

Ranitidine HCL State


Ranitidine HCL LogP


Ranitidine HCL Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Ranitidine HCL Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Ranitidine HCL Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Ranitidine HCL Absorption

Approximately 50% bioavailability orally.

Ranitidine HCL side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Ranitidine HCL Patient Information


Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Ranitidine HCL Organisms Affected

Humans and other mammals