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Sostril Brand names, Sostril Analogs

Sostril Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Sostril Chemical_Formula


Sostril RX_link

Sostril fda sheet

Sostril FDA

Sostril msds (material safety sheet)

Sostril MSDS

Sostril Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Sostril Molecular Weight

314.405 g/mol

Sostril Melting Point

69-70 oC

Sostril H2O Solubility

24.7 mg/mL

Sostril State


Sostril LogP


Sostril Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Sostril Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Sostril Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Sostril Absorption

Approximately 50% bioavailability orally.

Sostril side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Sostril Patient Information


Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Sostril Organisms Affected

Humans and other mammals