Quadrin

Quadrin Brand names, Quadrin Analogs

Quadrin Brand Names Mixture

Tritec (ranitidine bismuth citrate salt)

Quadrin Chemical_Formula

C₁₃H₂₂N₄O₃S

Quadrin RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Quadrin fda sheet

Quadrin FDA

Quadrin msds (material safety sheet)

Quadrin MSDS

Quadrin Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Quadrin Molecular Weight

314.405 g/mol

Quadrin Melting Point

69-70 ^oC

Quadrin H₂O Solubility

24.7 mg/mL

Quadrin State

Solid

Quadrin LogP

1.93

Quadrin Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Quadrin Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Quadrin Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Quadrin Absorption

Approximately 50% bioavailability orally.

Quadrin side effects and Toxicity

LD₅₀=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Quadrin Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Quadrin Organisms Affected

Humans and other mammals