PharmacyCodes



Ranitidin Basics en es it fr

Ranitidin Basics Brand names, Ranitidin Basics Analogs

Ranitidin Basics Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Ranitidin Basics Chemical_Formula

C13H22N4O3S

Ranitidin Basics RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Ranitidin Basics fda sheet

Ranitidin_Basics FDA

Ranitidin Basics msds (material safety sheet)

Ranitidin_Basics MSDS

Ranitidin Basics Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Ranitidin Basics Molecular Weight

314.405 g/mol

Ranitidin Basics Melting Point

69-70 oC

Ranitidin Basics H2O Solubility

24.7 mg/mL

Ranitidin Basics State

Solid

Ranitidin Basics LogP

1.93

Ranitidin Basics Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Ranitidin Basics Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Ranitidin Basics Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Ranitidin Basics Absorption

Approximately 50% bioavailability orally.

Ranitidin Basics side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Ranitidin Basics Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Ranitidin Basics Organisms Affected

Humans and other mammals