Normon

Normon Brand names, Normon Analogs

Normon Brand Names Mixture

Tritec (ranitidine bismuth citrate salt)

Normon Chemical_Formula

C₁₃H₂₂N₄O₃S

Normon RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Normon fda sheet

Normon FDA

Normon msds (material safety sheet)

Normon MSDS

Normon Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Normon Molecular Weight

314.405 g/mol

Normon Melting Point

69-70 ^oC

Normon H₂O Solubility

24.7 mg/mL

Normon State

Solid

Normon LogP

1.93

Normon Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Normon Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Normon Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Normon Absorption

Approximately 50% bioavailability orally.

Normon side effects and Toxicity

LD₅₀=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Normon Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Normon Organisms Affected

Humans and other mammals