PharmacyCodes



Ran H2 en es it fr

Ran H2 Brand names, Ran H2 Analogs

Ran H2 Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Ran H2 Chemical_Formula

C13H22N4O3S

Ran H2 RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Ran H2 fda sheet

Ran_H2 FDA

Ran H2 msds (material safety sheet)

Ran_H2 MSDS

Ran H2 Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Ran H2 Molecular Weight

314.405 g/mol

Ran H2 Melting Point

69-70 oC

Ran H2 H2O Solubility

24.7 mg/mL

Ran H2 State

Solid

Ran H2 LogP

1.93

Ran H2 Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Ran H2 Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Ran H2 Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Ran H2 Absorption

Approximately 50% bioavailability orally.

Ran H2 side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Ran H2 Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Ran H2 Organisms Affected

Humans and other mammals