Radin

Radin Brand names, Radin Analogs

Radin Brand Names Mixture

Tritec (ranitidine bismuth citrate salt)

Radin Chemical_Formula

C₁₃H₂₂N₄O₃S

Radin RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Radin fda sheet

Radin FDA

Radin msds (material safety sheet)

Radin MSDS

Radin Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Radin Molecular Weight

314.405 g/mol

Radin Melting Point

69-70 ^oC

Radin H₂O Solubility

24.7 mg/mL

Radin State

Solid

Radin LogP

1.93

Radin Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Radin Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Radin Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Radin Absorption

Approximately 50% bioavailability orally.

Radin side effects and Toxicity

LD₅₀=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Radin Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Radin Organisms Affected

Humans and other mammals