Gastrial

Gastrial Brand names, Gastrial Analogs

Gastrial Brand Names Mixture

Tritec (ranitidine bismuth citrate salt)

Gastrial Chemical_Formula

C₁₃H₂₂N₄O₃S

Gastrial RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Gastrial fda sheet

Gastrial FDA

Gastrial msds (material safety sheet)

Gastrial MSDS

Gastrial Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Gastrial Molecular Weight

314.405 g/mol

Gastrial Melting Point

69-70 ^oC

Gastrial H₂O Solubility

24.7 mg/mL

Gastrial State

Solid

Gastrial LogP

1.93

Gastrial Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Gastrial Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Gastrial Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Gastrial Absorption

Approximately 50% bioavailability orally.

Gastrial side effects and Toxicity

LD₅₀=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Gastrial Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Gastrial Organisms Affected

Humans and other mammals