Rantidine HCL

Rantidine HCL Brand names, Rantidine HCL Analogs

Rantidine HCL Brand Names Mixture

Tritec (ranitidine bismuth citrate salt)

Rantidine HCL Chemical_Formula

C₁₃H₂₂N₄O₃S

Rantidine HCL RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Rantidine HCL fda sheet

Rantidine_HCL FDA

Rantidine HCL msds (material safety sheet)

Rantidine_HCL MSDS

Rantidine HCL Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Rantidine HCL Molecular Weight

314.405 g/mol

Rantidine HCL Melting Point

69-70 ^oC

Rantidine HCL H₂O Solubility

24.7 mg/mL

Rantidine HCL State

Solid

Rantidine HCL LogP

1.93

Rantidine HCL Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Rantidine HCL Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Rantidine HCL Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Rantidine HCL Absorption

Approximately 50% bioavailability orally.

Rantidine HCL side effects and Toxicity

LD₅₀=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Rantidine HCL Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Rantidine HCL Organisms Affected

Humans and other mammals