Ranitidine Base en es it fr

Ranitidine Base Brand names, Ranitidine Base Analogs

Ranitidine Base Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Ranitidine Base Chemical_Formula


Ranitidine Base RX_link


Ranitidine Base fda sheet

Ranitidine_Base FDA

Ranitidine Base msds (material safety sheet)

Ranitidine_Base MSDS

Ranitidine Base Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Ranitidine Base Molecular Weight

314.405 g/mol

Ranitidine Base Melting Point

69-70 oC

Ranitidine Base H2O Solubility

24.7 mg/mL

Ranitidine Base State


Ranitidine Base LogP


Ranitidine Base Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Ranitidine Base Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Ranitidine Base Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Ranitidine Base Absorption

Approximately 50% bioavailability orally.

Ranitidine Base side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Ranitidine Base Patient Information


Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Ranitidine Base Organisms Affected

Humans and other mammals