Ranigen

Ranigen Brand names, Ranigen Analogs

Ranigen Brand Names Mixture

Tritec (ranitidine bismuth citrate salt)

Ranigen Chemical_Formula

C₁₃H₂₂N₄O₃S

Ranigen RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Ranigen fda sheet

Ranigen FDA

Ranigen msds (material safety sheet)

Ranigen MSDS

Ranigen Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Ranigen Molecular Weight

314.405 g/mol

Ranigen Melting Point

69-70 ^oC

Ranigen H₂O Solubility

24.7 mg/mL

Ranigen State

Solid

Ranigen LogP

1.93

Ranigen Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Ranigen Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Ranigen Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Ranigen Absorption

Approximately 50% bioavailability orally.

Ranigen side effects and Toxicity

LD₅₀=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Ranigen Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Ranigen Organisms Affected

Humans and other mammals