Ranitidina predilu Grif
Brand names,
Ranitidina predilu Grif
Analogs
Ranitidina predilu Grif
Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Ranitidina predilu Grif
Chemical_Formula
C13H22N4O3S
Ranitidina predilu Grif
RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranitidina predilu Grif
fda sheet
Ranitidina predilu Grif
msds (material safety sheet)
Ranitidina predilu Grif
Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranitidina predilu Grif
Molecular Weight
314.405 g/mol
Ranitidina predilu Grif
Melting Point
69-70 oC
Ranitidina predilu Grif
H2O Solubility
24.7 mg/mL
Ranitidina predilu Grif
State
Solid
Ranitidina predilu Grif
LogP
1.93
Ranitidina predilu Grif
Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranitidina predilu Grif
Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranitidina predilu Grif
Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranitidina predilu Grif
Absorption
Approximately 50% bioavailability orally.
Ranitidina predilu Grif
side effects and Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranitidina predilu Grif
Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranitidina predilu Grif
Organisms Affected
Humans and other mammals