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Rantacid Brand names, Rantacid Analogs

Rantacid Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Rantacid Chemical_Formula

C13H22N4O3S

Rantacid RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Rantacid fda sheet

Rantacid FDA

Rantacid msds (material safety sheet)

Rantacid MSDS

Rantacid Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Rantacid Molecular Weight

314.405 g/mol

Rantacid Melting Point

69-70 oC

Rantacid H2O Solubility

24.7 mg/mL

Rantacid State

Solid

Rantacid LogP

1.93

Rantacid Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Rantacid Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Rantacid Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Rantacid Absorption

Approximately 50% bioavailability orally.

Rantacid side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Rantacid Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Rantacid Organisms Affected

Humans and other mammals