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Ranitine Brand names, Ranitine Analogs

Ranitine Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Ranitine Chemical_Formula

C13H22N4O3S

Ranitine RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Ranitine fda sheet

Ranitine FDA

Ranitine msds (material safety sheet)

Ranitine MSDS

Ranitine Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Ranitine Molecular Weight

314.405 g/mol

Ranitine Melting Point

69-70 oC

Ranitine H2O Solubility

24.7 mg/mL

Ranitine State

Solid

Ranitine LogP

1.93

Ranitine Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Ranitine Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Ranitine Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Ranitine Absorption

Approximately 50% bioavailability orally.

Ranitine side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Ranitine Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Ranitine Organisms Affected

Humans and other mammals