Zantac

Zantac Brand names, Zantac Analogs

Zantac Brand Names Mixture

Tritec (ranitidine bismuth citrate salt)

Zantac Chemical_Formula

C₁₃H₂₂N₄O₃S

Zantac RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Zantac fda sheet

Zantac FDA

Zantac msds (material safety sheet)

Zantac MSDS

Zantac Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Zantac Molecular Weight

314.405 g/mol

Zantac Melting Point

69-70 ^oC

Zantac H₂O Solubility

24.7 mg/mL

Zantac State

Solid

Zantac LogP

1.93

Zantac Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Zantac Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Zantac Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Zantac Absorption

Approximately 50% bioavailability orally.

Zantac side effects and Toxicity

LD₅₀=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Zantac Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Zantac Organisms Affected

Humans and other mammals