Ranitidin Stada
Brand names,
Ranitidin Stada
Analogs
Ranitidin Stada
Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Ranitidin Stada
Chemical_Formula
C13H22N4O3S
Ranitidin Stada
RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranitidin Stada
fda sheet
Ranitidin Stada
msds (material safety sheet)
Ranitidin Stada
Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranitidin Stada
Molecular Weight
314.405 g/mol
Ranitidin Stada
Melting Point
69-70 oC
Ranitidin Stada
H2O Solubility
24.7 mg/mL
Ranitidin Stada
State
Solid
Ranitidin Stada
LogP
1.93
Ranitidin Stada
Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranitidin Stada
Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranitidin Stada
Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranitidin Stada
Absorption
Approximately 50% bioavailability orally.
Ranitidin Stada
side effects and Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranitidin Stada
Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranitidin Stada
Organisms Affected
Humans and other mammals