Ranitidin 1A Pharma
Brand names,
Ranitidin 1A Pharma
Analogs
Ranitidin 1A Pharma
Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Ranitidin 1A Pharma
Chemical_Formula
C13H22N4O3S
Ranitidin 1A Pharma
RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranitidin 1A Pharma
fda sheet
Ranitidin 1A Pharma
msds (material safety sheet)
Ranitidin 1A Pharma
Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranitidin 1A Pharma
Molecular Weight
314.405 g/mol
Ranitidin 1A Pharma
Melting Point
69-70 oC
Ranitidin 1A Pharma
H2O Solubility
24.7 mg/mL
Ranitidin 1A Pharma
State
Solid
Ranitidin 1A Pharma
LogP
1.93
Ranitidin 1A Pharma
Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranitidin 1A Pharma
Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranitidin 1A Pharma
Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranitidin 1A Pharma
Absorption
Approximately 50% bioavailability orally.
Ranitidin 1A Pharma
side effects and Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranitidin 1A Pharma
Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranitidin 1A Pharma
Organisms Affected
Humans and other mammals