Ranitidin

Ranitidin Brand names, Ranitidin Analogs

Ranitidin Brand Names Mixture

Tritec (ranitidine bismuth citrate salt)

Ranitidin Chemical_Formula

C₁₃H₂₂N₄O₃S

Ranitidin RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Ranitidin fda sheet

Ranitidin FDA

Ranitidin msds (material safety sheet)

Ranitidin MSDS

Ranitidin Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Ranitidin Molecular Weight

314.405 g/mol

Ranitidin Melting Point

69-70 ^oC

Ranitidin H₂O Solubility

24.7 mg/mL

Ranitidin State

Solid

Ranitidin LogP

1.93

Ranitidin Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Ranitidin Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Ranitidin Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Ranitidin Absorption

Approximately 50% bioavailability orally.

Ranitidin side effects and Toxicity

LD₅₀=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Ranitidin Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Ranitidin Organisms Affected

Humans and other mammals