Taural
Brand names,
Taural
Analogs
Taural
Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Taural
Chemical_Formula
C13H22N4O3S
Taural
RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Taural
fda sheet
Taural
msds (material safety sheet)
Taural
Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Taural
Molecular Weight
314.405 g/mol
Taural
Melting Point
69-70 oC
Taural
H2O Solubility
24.7 mg/mL
Taural
State
Solid
Taural
LogP
1.93
Taural
Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Taural
Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Taural
Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Taural
Absorption
Approximately 50% bioavailability orally.
Taural
side effects and Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Taural
Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Taural
Organisms Affected
Humans and other mammals