PharmacyCodes



Gastro en es it fr

Gastro Brand names, Gastro Analogs

Gastro Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Gastro Chemical_Formula

C13H22N4O3S

Gastro RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Gastro fda sheet

Gastro FDA

Gastro msds (material safety sheet)

Gastro MSDS

Gastro Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Gastro Molecular Weight

314.405 g/mol

Gastro Melting Point

69-70 oC

Gastro H2O Solubility

24.7 mg/mL

Gastro State

Solid

Gastro LogP

1.93

Gastro Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Gastro Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Gastro Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Gastro Absorption

Approximately 50% bioavailability orally.

Gastro side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Gastro Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Gastro Organisms Affected

Humans and other mammals