Crystal Violet base
Brand names,
Crystal Violet base
Analogs
Crystal Violet base
Brand Names Mixture
Crystal Violet base
Chemical_Formula
C25H30N3+
Crystal Violet base
RX_link
No information avaliable
Crystal Violet base
fda sheet
Crystal Violet base
msds (material safety sheet)
Crystal Violet base
Synthesis Reference
No information avaliable
Crystal Violet base
Molecular Weight
372.526 g/mol
Crystal Violet base
Melting Point
215 oC
Crystal Violet base
H2O Solubility
4 mg/mL
Crystal Violet base
State
Solid
Crystal Violet base
LogP
3.18
Crystal Violet base
Dosage Forms
Liquid; Tincture
Crystal Violet base
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Crystal Violet base
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Crystal Violet base
Absorption
No information avaliable
Crystal Violet base
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Crystal Violet base
Patient Information
Crystal Violet base
Organisms Affected
Yeast and other fungi, bacteria and protozoans