Atmonil
Brand names,
Atmonil
Analogs
Atmonil
Brand Names Mixture
Atmonil
Chemical_Formula
C25H30N3+
Atmonil
RX_link
No information avaliable
Atmonil
fda sheet
Atmonil
msds (material safety sheet)
Atmonil
Synthesis Reference
No information avaliable
Atmonil
Molecular Weight
372.526 g/mol
Atmonil
Melting Point
215 oC
Atmonil
H2O Solubility
4 mg/mL
Atmonil
State
Solid
Atmonil
LogP
3.18
Atmonil
Dosage Forms
Liquid; Tincture
Atmonil
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Atmonil
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Atmonil
Absorption
No information avaliable
Atmonil
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Atmonil
Patient Information
Atmonil
Organisms Affected
Yeast and other fungi, bacteria and protozoans