Vianin
Brand names,
Vianin
Analogs
Vianin
Brand Names Mixture
Vianin
Chemical_Formula
C25H30N3+
Vianin
RX_link
No information avaliable
Vianin
fda sheet
Vianin
msds (material safety sheet)
Vianin
Synthesis Reference
No information avaliable
Vianin
Molecular Weight
372.526 g/mol
Vianin
Melting Point
215 oC
Vianin
H2O Solubility
4 mg/mL
Vianin
State
Solid
Vianin
LogP
3.18
Vianin
Dosage Forms
Liquid; Tincture
Vianin
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Vianin
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Vianin
Absorption
No information avaliable
Vianin
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Vianin
Patient Information
Vianin
Organisms Affected
Yeast and other fungi, bacteria and protozoans