Crystal Violet USP
Brand names,
Crystal Violet USP
Analogs
Crystal Violet USP
Brand Names Mixture
Crystal Violet USP
Chemical_Formula
C25H30N3+
Crystal Violet USP
RX_link
No information avaliable
Crystal Violet USP
fda sheet
Crystal Violet USP
msds (material safety sheet)
Crystal Violet USP
Synthesis Reference
No information avaliable
Crystal Violet USP
Molecular Weight
372.526 g/mol
Crystal Violet USP
Melting Point
215 oC
Crystal Violet USP
H2O Solubility
4 mg/mL
Crystal Violet USP
State
Solid
Crystal Violet USP
LogP
3.18
Crystal Violet USP
Dosage Forms
Liquid; Tincture
Crystal Violet USP
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Crystal Violet USP
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Crystal Violet USP
Absorption
No information avaliable
Crystal Violet USP
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Crystal Violet USP
Patient Information
Crystal Violet USP
Organisms Affected
Yeast and other fungi, bacteria and protozoans