Hexamethyl Violet
Brand names,
Hexamethyl Violet
Analogs
Hexamethyl Violet
Brand Names Mixture
Hexamethyl Violet
Chemical_Formula
C25H30N3+
Hexamethyl Violet
RX_link
No information avaliable
Hexamethyl Violet
fda sheet
Hexamethyl Violet
msds (material safety sheet)
Hexamethyl Violet
Synthesis Reference
No information avaliable
Hexamethyl Violet
Molecular Weight
372.526 g/mol
Hexamethyl Violet
Melting Point
215 oC
Hexamethyl Violet
H2O Solubility
4 mg/mL
Hexamethyl Violet
State
Solid
Hexamethyl Violet
LogP
3.18
Hexamethyl Violet
Dosage Forms
Liquid; Tincture
Hexamethyl Violet
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Hexamethyl Violet
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Hexamethyl Violet
Absorption
No information avaliable
Hexamethyl Violet
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Hexamethyl Violet
Patient Information
Hexamethyl Violet
Organisms Affected
Yeast and other fungi, bacteria and protozoans