Axuris
Brand names,
Axuris
Analogs
Axuris
Brand Names Mixture
Axuris
Chemical_Formula
C25H30N3+
Axuris
RX_link
No information avaliable
Axuris
fda sheet
Axuris
msds (material safety sheet)
Axuris
Synthesis Reference
No information avaliable
Axuris
Molecular Weight
372.526 g/mol
Axuris
Melting Point
215 oC
Axuris
H2O Solubility
4 mg/mL
Axuris
State
Solid
Axuris
LogP
3.18
Axuris
Dosage Forms
Liquid; Tincture
Axuris
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Axuris
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Axuris
Absorption
No information avaliable
Axuris
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Axuris
Patient Information
Axuris
Organisms Affected
Yeast and other fungi, bacteria and protozoans