Violet CP
Brand names,
Violet CP
Analogs
Violet CP
Brand Names Mixture
Violet CP
Chemical_Formula
C25H30N3+
Violet CP
RX_link
No information avaliable
Violet CP
fda sheet
Violet CP
msds (material safety sheet)
Violet CP
Synthesis Reference
No information avaliable
Violet CP
Molecular Weight
372.526 g/mol
Violet CP
Melting Point
215 oC
Violet CP
H2O Solubility
4 mg/mL
Violet CP
State
Solid
Violet CP
LogP
3.18
Violet CP
Dosage Forms
Liquid; Tincture
Violet CP
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Violet CP
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Violet CP
Absorption
No information avaliable
Violet CP
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Violet CP
Patient Information
Violet CP
Organisms Affected
Yeast and other fungi, bacteria and protozoans