Hecto Violet R
Brand names,
Hecto Violet R
Analogs
Hecto Violet R
Brand Names Mixture
Hecto Violet R
Chemical_Formula
C25H30N3+
Hecto Violet R
RX_link
No information avaliable
Hecto Violet R
fda sheet
Hecto Violet R
msds (material safety sheet)
Hecto Violet R
Synthesis Reference
No information avaliable
Hecto Violet R
Molecular Weight
372.526 g/mol
Hecto Violet R
Melting Point
215 oC
Hecto Violet R
H2O Solubility
4 mg/mL
Hecto Violet R
State
Solid
Hecto Violet R
LogP
3.18
Hecto Violet R
Dosage Forms
Liquid; Tincture
Hecto Violet R
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Hecto Violet R
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Hecto Violet R
Absorption
No information avaliable
Hecto Violet R
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Hecto Violet R
Patient Information
Hecto Violet R
Organisms Affected
Yeast and other fungi, bacteria and protozoans