Hexamethylpararosaniline chloride
Brand names,
Hexamethylpararosaniline chloride
Analogs
Hexamethylpararosaniline chloride
Brand Names Mixture
Hexamethylpararosaniline chloride
Chemical_Formula
C25H30N3+
Hexamethylpararosaniline chloride
RX_link
No information avaliable
Hexamethylpararosaniline chloride
fda sheet
Hexamethylpararosaniline chloride
msds (material safety sheet)
Hexamethylpararosaniline chloride
Synthesis Reference
No information avaliable
Hexamethylpararosaniline chloride
Molecular Weight
372.526 g/mol
Hexamethylpararosaniline chloride
Melting Point
215 oC
Hexamethylpararosaniline chloride
H2O Solubility
4 mg/mL
Hexamethylpararosaniline chloride
State
Solid
Hexamethylpararosaniline chloride
LogP
3.18
Hexamethylpararosaniline chloride
Dosage Forms
Liquid; Tincture
Hexamethylpararosaniline chloride
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Hexamethylpararosaniline chloride
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Hexamethylpararosaniline chloride
Absorption
No information avaliable
Hexamethylpararosaniline chloride
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Hexamethylpararosaniline chloride
Patient Information
Hexamethylpararosaniline chloride
Organisms Affected
Yeast and other fungi, bacteria and protozoans