Paper Blue R
Brand names,
Paper Blue R
Analogs
Paper Blue R
Brand Names Mixture
Paper Blue R
Chemical_Formula
C25H30N3+
Paper Blue R
RX_link
No information avaliable
Paper Blue R
fda sheet
Paper Blue R
msds (material safety sheet)
Paper Blue R
Synthesis Reference
No information avaliable
Paper Blue R
Molecular Weight
372.526 g/mol
Paper Blue R
Melting Point
215 oC
Paper Blue R
H2O Solubility
4 mg/mL
Paper Blue R
State
Solid
Paper Blue R
LogP
3.18
Paper Blue R
Dosage Forms
Liquid; Tincture
Paper Blue R
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Paper Blue R
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Paper Blue R
Absorption
No information avaliable
Paper Blue R
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Paper Blue R
Patient Information
Paper Blue R
Organisms Affected
Yeast and other fungi, bacteria and protozoans