gentian violet gr
Brand names,
gentian violet gr
Analogs
gentian violet gr
Brand Names Mixture
gentian violet gr
Chemical_Formula
C25H30N3+
gentian violet gr
RX_link
No information avaliable
gentian violet gr
fda sheet
gentian violet gr
msds (material safety sheet)
gentian violet gr
Synthesis Reference
No information avaliable
gentian violet gr
Molecular Weight
372.526 g/mol
gentian violet gr
Melting Point
215 oC
gentian violet gr
H2O Solubility
4 mg/mL
gentian violet gr
State
Solid
gentian violet gr
LogP
3.18
gentian violet gr
Dosage Forms
Liquid; Tincture
gentian violet gr
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
gentian violet gr
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
gentian violet gr
Absorption
No information avaliable
gentian violet gr
side effects and Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
gentian violet gr
Patient Information
gentian violet gr
Organisms Affected
Yeast and other fungi, bacteria and protozoans